A Voice from the Past - Methodius

This in truth, must be called most excellent and praiseworthy, which God Himself considers excellent, even if it be despised and scoffed at by all. For things are not what men think them to be.

Methodius, ?-311 AD, Work Against Porphyry, Fragment 1, (translated by Rev. William R. Clark, Ante-Nicene Fathers, Alexander Roberts and James Donaldson, Hendrickson Publishers, 2004, Vol. 6, p. 382).

Is there a conflict between God's truth and what others consider to be true? How do we deal with it?